Making the Connection Between Cancer and Mold Mycotoxins

By Mold Medical Expert Donald Dennis, MD, FACS
September 26, 2011

Mycotoxins are low molecular weight  (250-500 daltons), non-volatile compounds produced by filamentous molds (fungi) of the genera Fusarium, Myrothecium, Tricoderma, Stachybotrys, Aspergillus, Penicillium, Cladosporium, Alternaria, Mucor and others. These fungi are saprobic causing a cottony growth on organic substances. Mycotoxins are oily, insoluble in water, and soluble in alcohol and propylene glycol. Some mycotoxins cling to the surface of mold spores; others are found inside spores. Most mycotoxins are odorless, and none are visible as aerosols. There are over 400 mycotoxins; the most common “families” are Tricothecenes, Aflotoxins, and Ochratoxins. The most toxic fungi due to their toxins are Stachybotrys, Aspergillus, Fusarium, Penicillium, Trichoderma, and others.

T-2, a mycotoxin produced by Fusarium, is the most toxic of the Trichothecenes. It can persist for years at room temperature. It grows well at cold temperatures and contaminates grains in storage silos. Trichothecenes have a peppery odor. These toxins can enter the body by breathing, skin contact, and ingestion.

Mycotxins can be so deadly they have been used as weapons. In the 1970’s controversial evidence suggested that Communists (Russia and ally states) had attacked southeast Asia with trichothecene mycotoxins (‘yellow rain’), resulting in the deaths of thousands. Mycotoxins have higher toxicity than nerve gas. The people had symptoms including vomiting, dizziness, seizures, coughing blood, respiratory distress, low blood pressure, and blisters. Survivors were ill for a long time with rashes, joint pain, fatigue, and memory problems. Between 1975 – 1982, attacks with mycotoxins (yellow rain) killed 6,000+ Llaotians, 1,000 Cambodians, and 3,000 Afghans.

Another example of a highly dangerous mycotoxin is Aflatoxin, a naturally occuring mycotoxin produced by Aspergillus, it will fluoresce under ultraviolet light and is soluble in alcohol. Aflatoxin B1 is the most studied because it is one of the MOST potent carcinogens known. In the home, Aflatoxins occur in nuts, cereals, and rice under high humidity conditions often present in the storage containers. Two major Aspergillus species produce aflatoxins. A. flavus ( Aflatoxin B) and A. parasiticus (Aflatoxin B & G). Aflatoxins are acutely toxic, immunosuppressive, mutagenic, teratgenic and carcinogenic compounds. The main target organ for toxicity and carcinogenicity is the liver (Bulletin of the WHO, 1999).

Mycotoxins destroy virtually every system in the human body by:

  • Inhibit protein synthesis, DNA synthesis, and mitochondrial protein synthesis. They can erode the myelin sheath nerve covering causing many neurological symptoms, seizures, headaches, muscle weakness, twitches, etc.
  • Impair ribosome function.
  • Cause immunosuppression which then allows the intrusion of opportunistic bacterial and viral infections to occur, especially Epstein Barr (chronic fatigue syndrome), herpes and other CMV viruses.
  • Chronic low dose exposure to mycotoxins can cause immune suppression, low white blood cell counts (toxic aleukia), leukemia, lymphoma, and multiple other malignancies. Effects accumulate with repeated exposures. Low doses can cause low white blood cells count in the gut which represents 70% of the immune system.

Mycotoxins are Found in a Large Percentage of Cancers

Cancer Type Instances Type of Mycotoxin Present
Astrocytomas 9/13 Ochratoxin Aflatoxin
Breast 3/3 Ochratoxin
ALS 1/1 Aflatoxin
Mesothelioma 1/1 Ochratoxin
Lung Adenocarcinoma 1/1 Aflatoxin
Bronchial Alevolar CA 1/1 Ochratoxin
Renal Cell Carcinoma 4/4 Ochratoxin A in urine & tumor
Uterine 5/5 Aflatoxin
Uterine 2/5 Ochratoxin in urine & tissue
Uterine 1/5 Trichotecenes in urine & tissue
Esthesioneurbobastoma 1/1 Ochratoxin in urine & tissue

In 27 Cancer Cases out of 31 Mycotoxins were present
27/31 = 87%

Mycotoxions are found in a large percentage of cancers due to the fact that they are known to cause cancer in animals by the displacement of DNA base pairs. There environmental fungal control is essential to protect the environment from high levels of mycotoxins. Humidity control of less than 50%, control of any cause of moisture intrusion, removal of everything that got wet, treating surfaces with a good non-toxic antifungal that will remove the mycotoxins.

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Other Conditions Caused by Mycotoxins
  • Vertigo & Dizziness, Deafness
  • Gastric Reflux Disease (GERD)
  • Candidiasis
  • Pulmonary Aspergillosis
  • Irritable Bowel Syndrome (IBS)
  • Diarrhea, Bloating, Gas
  • Muscle Weakness
  • Polycystic Ovary Syndrome
  • Cognitive Dysfunction
  • Memory Loss
  • Cardiovascular Disease
  • Cardiac Arrhythmia
  • Flu-like Symptoms
  • Tremors
  • Seizures
  • Immune Suppression
  • IgG Subclass deficiency
  • Arthritis
  • Fibromyalgia
  • Chronic Fatigue
  • Cough, Asthma
  • Bronchitis
  • Muscle and Joint Pain
  • Severe headache
  • Multiple Chemical Sensitivities (MCS)
  • Food Allergies
  • Pituitary Damage
  • Multiple Hormone Deficiencies (Thyroid,Cortisol, Growth Hormone, Estrogen, Testosterone etc.)
  • Skin Disorders, Psoriasis, Rashes
  • Muscle pain and Weakness
  • Muscle Paralysis
  • Bladder Paralysis
  • Systemic Inflammation
  • Hair Loss

Micro Balance Mold Concentrate has been shown by Real Time Labs to remove mycotoxins.

References:
Dennis Hooper, MD, PhD, RealTime Lab.

Human mycotoxin levels can be measured in urine and tissue by Real Time Lab. http://www.realtimelab.com/
Article References:
McCrady,E. Mold Reporter Vol.1,No.4
.Bulletin of the WHO, 9-1-1999
Croft, W.A. et al. Airborne outbreak of Trichothecenes toxicosis. Atmospheric environment, 1986,20: 549-552
Medical Management of Biological Casualties Handbook (MMBC), 1999, p.41-43.